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Thursday, May 31, 2012

Supplements: Tyrosine

Tyrosine is an amino acid and is used in protein supplements to treat an inherited disorder called phenylketonuria (PKU). People who have this problem can’t process phenylalanine properly, so as a result they can’t make tyrosine. To meet their bodies’ needs, supplemental tyrosine is given.  Phenylalanine converts to L Tyrosine, followed by L-dopa which in turns is metabolized to dopamine which can convert into norepinephrine and then to epinephrine.  It's defiantly a mind power supplement.

Some people also apply tyrosine to the skin to reduce age-related wrinkles.
It can improve alertness in people who experience lack of sleep.
Can be used to treat:

  • moderate depression
  • ADD
  • ADHD  Awesome 8 part blog series on Tyrosine and ADHD
  • Stress
  • Sleep Deprevation
  • Narcolepsy
  • Erectile Dysfunction (ED)
  • loss of interest in sex
  • Premenstrual syndrome (PMS)
  • Parkinson's disease
  • Chronic fatigue syndrome (CFS)
  • Alzheimer's disease
  • Heart disease
  • Erectile dysfunction (ED)

  • Schizophrenia
Side Effects:
  • Heartburn
  • Nausea
  • Fatigue
  • Joint Pain
Overactive thyroid (hyperthyroidism) or Graves disease: The body uses tyrosine to make thyroxine, a thyroid hormone. Taking extra tyrosine might increase thyroxine levels too much, making hyperthyroidism and Graves disease worse. If you have one of these conditions, don’t take tyrosine supplements.

Do not take while pregnant or breast feeding, as effects are unknown.

I've found conflicting information on recommended dosage.  Doses of 150 mg are recommended for start.  People report Tyrosine Shots starting at 500 mg daily, increasing in increments of 500 mg increments up to 2000-3000 mg is effective for increased alertness and fighting fatigue.  My guess is start with 500 mg, since it's hard to get capsules less than 350mg with typical capsule size at 500 mg.

It is most effective when paired with protein.  It crosses the blood/brain barrier quickly, so effects are fairly quick.

L Tyrosine side effects can include over-stimulation, restlessness, anxiety, and insomnia. Heart palpitations or arrhythmias are potential side effects that occur from high doses of tyrosine. These can occur in sensitive individuals in as low a dose as 200 to 500 mg.  Doses above 500 mg can cause anxiety.

Talk to your doctor before starting Tyrosine supplements, as there are negative drug interactions.

You can pick up a bottle of 500 mg capsules for under $10, but I'm having a hard time finding anything under 350 mg capsules.

Foods containing Tyrosine:egg, dairy, seaweed, fish, shellfish, wild game, poultry, beef, bison, pork, crustaceans, mollusks, soy, leafy greens, kidney beans, tofu.  A serving of any of these contains over 1000 mg.  Check out the monster list


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